Volatile components of Dillenia reticulata King (Dilleniaceae) essential oil and their cytotoxicity
نویسندگان
چکیده
ABSTRACT. This work aimed to investigate, for the first time, chemical composition and cytotoxicity of Dillenia reticulata King’s essential oil. The oil was obtained through hydrodistillation, its volatile components were analyzed gas chromatography (GC-FID) chromatography-mass spectrometry (GC-MS) techniques. Twelve components, which constitutes more than 99.49% content, successfully identified. most prominent bicyclogermacrene (44.18%), germacrene D (14.49%), ?-gurjunene (12.59%), elemol (12.25%). evaluated using an MTT assay. exhibited against three cancer cell lines are HepG2, MCF7 A549 with IC50 values ranging from 61.5-68.5 ?g/mL. present study highlights potential as alternative development chemopreventive or cosmetic agents pharmaceutical industry.
 
 KEY WORDS: reticulata, Dilleniaceae, Essential oil, Cytotoxicity, Bicyclogermacrene
 Bull. Chem. Soc. Ethiop. 2023, 37(1), 245-249. DOI: https://dx.doi.org/10.4314/bcse.v37i1.19
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ژورنال
عنوان ژورنال: Bulletin of The Chemical Society of Ethiopia
سال: 2022
ISSN: ['1011-3924', '1726-801X']
DOI: https://doi.org/10.4314/bcse.v37i1.19